After installation of APS application (for example, Wordress) at webspace root directory
http://domain.tld/ on Windows-based web hosting, website handlers in IIS are corrupted.
The behavior was considered as internal software issue #PPA-3186.
The fix is considered to be included in one of the next PA updates.
Please use provided ID to track maintenance in Plesk Automation release notes.
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Change supported web scripting settings in hosting settings for domain in CCP and save changes.